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Lik Sprava ; (1-2): 27-35, 2014.
Article Ru | MEDLINE | ID: mdl-24908956

Was examined 92 patients with congestive heart failure III-IV FC with fraction of emission left ventricle < 45% against coronary artery disease. Patients of control group received basic therapy (according to recommendations of the Ukrainian society of cardiology), the 1 group--in addition received a preparation of Vazonat within 15 days intravenously in a dose of 1000 mg a day further are out-patient within 1 month on 250 mg 3 times per os; the 2 group--under the same scheme a preparation of Vazonat and a day tranquilizer of Adapto in a dose of 500 mg twice a day throughout all term of supervision. It is established that addition of Vazonat to basic treatment leads to additional effect concerning improvement of indicators cardio-hemodynamic, to improvement congestive functions. Joint appointment of preparations of Vazonat and Adaptol against basic treatment leads to more expressed improvement congestive functions, to progressive reduction of degree of trouble, depression.


Anti-Anxiety Agents/therapeutic use , Biureas/therapeutic use , Cardiovascular Agents/therapeutic use , Heart Failure/drug therapy , Methylhydrazines/therapeutic use , Psychophysiologic Disorders/drug therapy , Aged , Anti-Anxiety Agents/administration & dosage , Anti-Anxiety Agents/adverse effects , Biureas/administration & dosage , Biureas/adverse effects , Cardiovascular Agents/administration & dosage , Cardiovascular Agents/adverse effects , Cognition/drug effects , Drug Therapy, Combination , Echocardiography , Exercise Test , Heart Failure/pathology , Heart Failure/physiopathology , Heart Failure/psychology , Hemodynamics/drug effects , Humans , Methylhydrazines/administration & dosage , Methylhydrazines/adverse effects , Middle Aged , Myocardial Contraction/drug effects , Myocardium/pathology , Neuropsychological Tests , Psychophysiologic Disorders/physiopathology , Psychophysiologic Disorders/psychology , Severity of Illness Index , Treatment Outcome
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